Thermo Fisher Scientific NALP8 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NALP8, validated for Western blot use. Antigen affinity purified, supplied as liquid at 1 mg/mL in PBS with sodium azide. Recommended positive control: human colon tissue lysate. For research use only.
- 카탈로그번호
- PA521024
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the amino terminus of human NALP8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154618 |
Product Specific Information
- Suggested positive control: human colon tissue lysate
- PA5-21024 can be used with blocking peptide PEP-1138
Target Information
NALP proteins are cytoplasmic proteins forming a subfamily within the CATERPILLER family and play a crucial role in cell proliferation and reproduction.
NALP8 has:
- A C-terminal leucine-rich repeat (LRR) region
- An N-terminal Pyrin domain (PYD)
- A NACHT domain and a NACHT-associated domain
It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting involvement in reproduction.
Interestingly, NALP8 appears to be universal in mammals except for rodents, implying that the gene may have been lost during evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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