Thermo Fisher Scientific Phospho-IGF1R beta (Tyr1135, Tyr1136) Recombinant Rabbit Monoclonal Antibody (15H10L8)
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IGF1R β의 Tyr1135/1136 인산화를 인식하는 재조합 토끼 단클론 항체. Western blot에 적합하며 높은 특이성과 재현성을 제공. Expi293 시스템에서 발현된 IgG 형식, Protein A 정제, 0.5 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 15H10L8 |
| Immunogen | Phosphopeptide corresponding to amino acids 1131–1140 of human IGF1R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532368 |
Product Specific Information
- Intact IgG appears on a non-reducing gel as a ~150 kDa band, and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits.
- Clones are screened to select the best candidates for production.
- Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
IGF-1R (Insulin-like Growth Factor-1 Receptor)
- Composed of alpha- and beta-subunits linked by disulfide bonds in a β-α-α-β configuration.
- The alpha-subunit is extracellular, while the beta-subunit spans the membrane and contains intrinsic tyrosine kinase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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