Thermo Fisher Scientific Phospho-IGF1R beta (Tyr1135, Tyr1136) Recombinant Rabbit Monoclonal Antibody (15H10L8)

Applications

Western Blot (WB)

• Tested Dilution: 1–3 µg/mL
• View 1 publication

Product Specifications

Product Specific Information

• Intact IgG appears on a non-reducing gel as a ~150 kDa band, and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits.
• Clones are screened to select the best candidates for production.
• Advantages include:
  • Better specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulations
  • Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

IGF-1R (Insulin-like Growth Factor-1 Receptor)

• Composed of alpha- and beta-subunits linked by disulfide bonds in a β-α-α-β configuration.
• The alpha-subunit is extracellular, while the beta-subunit spans the membrane and contains intrinsic tyrosine kinase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.