Thermo Fisher Scientific CD204 Monoclonal Antibody (2F8)
CD204 단백질을 인식하는 Rat IgG2b 모노클로날 항체로, WB, IHC, Flow Cytometry, ELISA, IP, Functional Assay 등에 사용 가능. 저엔도톡신, 무보존제 포뮬레이션으로 연구용에 적합. 다양한 형광 및 비오틴 접합 형식 제공.
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Thermo Fisher Scientific CD204 Monoclonal Antibody (2F8)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:50–1:100 |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| Functional Assay | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Fish, Mouse, Pig |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F8 |
| Immunogen | RAW264 cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538005 |
Available Conjugated Formats
Product Specific Information
- In Western blot, recognizes CD204 in J774 cells under non-reducing conditions only.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
- Low-endotoxin, preservative-free formulation.
- Endotoxin level: <0.01 EU/µg.
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three isoforms (types 1, 2, and 3) generated by alternative splicing. These macrophage-specific trimeric integral membrane glycoproteins are involved in physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
Type 1 and 2 isoforms mediate endocytosis of modified LDLs, while type 3 is trapped in the endoplasmic reticulum and inhibits the function of types 1 and 2, suggesting regulatory roles in scavenger receptor activity.
Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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