
Thermo Fisher Scientific CD204 Monoclonal Antibody (2F8), PE
PE 형광 표지된 CD204 단클론 항체(2F8)로, 마우스, 어류, 돼지 시료에 반응합니다. Flow Cytometry에 적합하며, Protein G로 정제되었습니다. 동결 건조 형태로 제공되며, 4°C 암소 보관이 권장됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fish, Mouse, Pig |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F8 |
| Immunogen | RAW264 cell line |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA, 5% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538007 |
Additional Formats
- Unconjugated (MA5-16492)
- Biotin (MA5-16493)
- FITC (MA1-81060)
- Custom conjugation available
Product Specific Information
- Reconstitute with 1 mL of distilled water.
- After reconstitution, store undiluted at 4°C in the dark.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
- Rat anti-Mouse CD204 antibody, clone 2F8, recognizes murine scavenger receptor class A (SRA) type I and II (CD204).
Target Information
CD204 encodes class A macrophage scavenger receptors, including three isoforms (1, 2, 3) generated by alternative splicing. These macrophage-specific trimeric membrane glycoproteins are involved in physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
- Isoforms 1 and 2: functional receptors mediating endocytosis of modified LDLs.
- Isoform 3: non-functional in LDL uptake due to altered intracellular processing, retained in the endoplasmic reticulum, and exerts a dominant negative effect on other isoforms.
- Associated diseases: Barrett Esophagus, Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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