Thermo Fisher Scientific CD204 Monoclonal Antibody (2F8), FITC
FITC로 표지된 Rat monoclonal anti-CD204 항체(클론 2F8)는 Flow Cytometry에 적합하며 Mouse, Pig, Fish에 반응합니다. 단백질 G로 정제된 액상 형태로 제공되며, 4°C 또는 -20°C에서 보관 가능합니다. 대식세포 관련 연구에 유용합니다.
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Thermo Fisher Scientific CD204 Monoclonal Antibody (2F8), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:10–1:50
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fish, Mouse, Pig |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F8 |
| Immunogen | RAW264 cell line |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles). Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538006 |
Additional Formats
- Unconjugated (MA5-16492)
- Biotin (MA5-16493)
- PE (MA5-16496)
- Request custom conjugation
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Rat anti-Mouse CD204 antibody, clone 2F8 recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204.
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three isoforms (1, 2, 3) generated by alternative splicing. These macrophage-specific trimeric integral membrane glycoproteins are involved in processes such as atherosclerosis, Alzheimer’s disease, and host defense.
- Isoforms type 1 and 2 mediate endocytosis of modified LDLs.
- Isoform type 3 does not internalize modified LDL and is retained in the endoplasmic reticulum.
- Type 3 can inhibit function of types 1 and 2, suggesting a regulatory mechanism for scavenger receptor activity.
Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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