Thermo Fisher Scientific COLQ Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 276-455 of human COLQ (NP_005668.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COLQ,uniProtId:Q9Y215-1,ncbiNodeId:9606,antigenRange:276-455,antigenLength:455,antigenImageFileName:PA5-109572_COLQ_Q9Y215-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109572_COLQ_Q9Y215-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854983

Product Specific Information

Immunogen sequence: MGPKGERGFP GPPGRCLCGP TMNVNNPSYG ESVYGPSSPR VPVIFVVNNQ EELERLNTQN AIAFRRDQRS LYFKDSLGWL PIQLTPFYPV DYTADQHGTC GDGLLQPGEE CDDGNSDVGD DCIRCHRAYC GDGHRHEGVE DCDGSDFGYL TCETYLPGSY GDLQCTQYCY IDSTPCRYFT

Target Information

COLQ (collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase), also known as EAD, is a 455 amino acid protein that localizes to the end plate of skeletal muscle. COLQ anchors the catalytic subunits of asymmetric AChE (acetylcholinesterase) to the basal lamina at the neuromuscular junctions of vertebrates. Mutations of COLQ lead to congenital myasthenic syndromes which are rare autosomal recessive diseases characterized by general weakness increased by exertion, ophthalmoplegia and refractoriness to anticholinesterase drugs. Eight isoforms exist due to alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.