Thermo Fisher Scientific COLQ Polyclonal Antibody
COLQ 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Mouse 및 Rat 시료에서 Western blot과 ELISA에 적합합니다. 고순도 Affinity Chromatography로 정제되었으며, 안정적인 PBS/glycerol buffer로 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 276–455 of human COLQ (NP_005668.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854983 |
Product Specific Information
Immunogen sequence:
MGPKGERGFP GPPGRCLCGP TMNVNNPSYG ESVYGPSSPR VPVIFVVNNQ EELERLNTQN AIAFRRDQRS LYFKDSLGWL PIQLTPFYPV DYTADQHGTC GDGLLQPGEE CDDGNSDVGD DCIRCHRAYC GDGHRHEGVE DCDGSDFGYL TCETYLPGSY GDLQCTQYCY IDSTPCRYFT
Target Information
COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase) is a 455-amino-acid protein that localizes to the end plate of skeletal muscle.
It anchors the catalytic subunits of asymmetric AChE to the basal lamina at neuromuscular junctions.
Mutations in COLQ cause congenital myasthenic syndromes, rare autosomal recessive diseases characterized by muscle weakness, ophthalmoplegia, and resistance to anticholinesterase drugs.
Eight isoforms exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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