Thermo Fisher Scientific COG2 Polyclonal Antibody
COG2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. Affinity Chromatography로 정제된 액상 형태로, PBS/glycerol buffer에 보관. -20°C에서 보관하며 반복 동결/해동은 피해야 함.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–280 of human COG2 (NP_031383.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854978 |
Product Specific Information
Immunogen sequence:
MEKSRMNLPK GPDTLCFDKD EFMKEDFDVD HFVSDCRKRV QLEELRDDLE LYYKLLKTAM VELINKDYAD FVNLSTNLVG MDKALNQLSV PLGQLREEVL SLRSSVSEGI RAVDERMSKQ EDIRKKKMCV LRLIQVIRSV EKIEKILNSQ SSKETSALEA SSPLLTGQIL ERIATEFNQL QFHAVQSKGM PLLDKVRPRI AGITAMLQQS LEGLLLEGLQ TSDVDIIRHC LRTYATIDKT RDAEALVGQV LVKPYIDEVI IEQFVESHPN GLQVMYNKLL
Target Information
The structure and function of the Golgi apparatus is controlled by multi-protein complexes involved in glycosylation and vesicular transport.
The conserved oligomeric Golgi (COG) complex includes subcomplexes LDLC, SEC34, and GTT, each essential for Golgi operation.
COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730 amino acid component localized to the cytoplasmic side of the Golgi apparatus.
It plays a key role in maintaining Golgi morphology, ribbon formation, and vesicular transport.
Abnormal COG2 function can lead to cell death, indicating its importance in cell viability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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