Thermo Fisher Scientific Methotrexate Polyclonal Antibody
Methotrexate를 인식하는 양(Sheep) 유래 다클론 항체로 ELISA 등 연구용 분석에 적합. 화학적 항원 Methotrexate에 특이적 반응. 액상 형태로 제공되며 장기 보관 시 -20°C에서 냉동 보존 권장. 항암 및 면역억제제 연구에 활용 가능.
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Thermo Fisher Scientific Methotrexate Polyclonal Antibody
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Methotrexate (4-amino-10-methylpteroyl-L-glutamic acid) conjugated via the carboxyl groups of the glutamic acid residue to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2550590 |
Product Specific Information
Sheep anti-methotrexate antibody recognizes Methotrexate, a drug originally manufactured as a chemotherapeutic agent for the treatment of a number of cancers.
Target Information
Methotrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. It binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis, and subsequently inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of action is unclear.
[National Center for Biotechnology Information. PubChem Compound Database; CID=126941]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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