Thermo Fisher Scientific Androgen Receptor Recombinant Rabbit Monoclonal Antibody (DHTR, 4445R)
Androgen Receptor를 인식하는 재조합 토끼 단클론 항체로, IHC(P) 검증 완료. 인간 시료 반응성, HEK293 발현 시스템 기반. Protein A/G 정제, 200 µg/mL 농도. 4°C 보관, 연구용 전용.
- 카탈로그번호
- 367-RBM5-P1
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Androgen Receptor Recombinant Rabbit Monoclonal Antibody (DHTR, 4445R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | DHTR, 4445R |
| Immunogen | Synthetic peptide corresponding to residues (within aa 1–100) of Androgen Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors.
It is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT).
Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and stimulates transcription of androgen-responsive genes.
AR signaling plays a key role in development and function of male reproductive organs (prostate, epididymis) and also affects nonreproductive organs (muscle, hair follicles, brain).
Abnormalities in AR signaling are linked to diseases such as prostate cancer, Kennedy’s disease, and male infertility.
Mutations in this gene are associated with complete androgen insensitivity (CAIS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.