Thermo Fisher Scientific HOXC11 Monoclonal Antibody (OTI2H9), TrueMAB
Human HOXC11 단백질을 인식하는 mouse monoclonal antibody로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. TrueMAB 형식으로 고순도 affinity chromatography 정제. Lyophilized 형태로 -20°C 보관, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–304 of human HOXC11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The HOXC11 gene belongs to the homeobox family, encoding transcription factors critical for morphogenesis in multicellular organisms.
Mammals possess four homeobox gene clusters — HOXA, HOXB, HOXC, and HOXD — located on different chromosomes.
HOXC11 is part of the HOXC cluster on chromosome 12 and binds to the promoter element of lactase-phlorizin hydrolase. It may play a role in early intestinal development.
An alternatively spliced variant encoding a shorter isoform has been described, though its full-length structure remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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