Thermo Fisher Scientific SSH2 Polyclonal Antibody
SSH2 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western blot에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 액상 형태로 제공됩니다. 항원 친화 크로마토그래피로 정제되어 높은 순도(>95%)를 보장합니다. 연구용으로만 사용됩니다.
- 판매단위
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Thermo Fisher Scientific SSH2 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:200–1:500
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human SSH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720192 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
SSH2 (slingshot homolog 2) is a 1,423 amino acid protein localized to the cytoplasm and cytoskeleton. It is a human homolog of the Drosophila slingshot (ssh) protein and contains a tyrosine-protein phosphatase domain. SSH2 regulates Actin filament dynamics via dephosphorylation of target proteins such as Cofilin, which mediate Actin filament assembly and disassembly. Four isoforms of SSH2 exist due to alternative splicing. The SSH2 gene maps to human chromosome 17, which encodes over 1,200 genes and includes tumor suppressors p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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