Thermo Fisher Scientific IFI16 Polyclonal Antibody
Human IFI16 단백질을 표적으로 하는 rabbit polyclonal antibody로, WB, ICC/IF, ChIP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. 세포 내 IFI16 관련 연구 및 면역 반응 분석에 활용 가능.
- 카탈로그번호
- PA576462
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IFI16 Polyclonal Antibody
Thermo Fisher Scientific IFI16 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| ChIP assay (ChIP) | 2.5 µg/10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human IFI16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720189 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
IFI16 (gamma-interferon-inducible protein 16) binds double-stranded DNA, preferentially to supercoiled and cruciform DNA structures. It participates in transcriptional regulation and acts as a transcriptional repressor. IFI16 may regulate hematopoietic differentiation and cellular proliferation by modulating p53/TP53 and retinoblastoma protein functions. It plays a key role in innate immune response by recognizing viral dsDNA and activating TMEM173/STING-mediated IFN-beta induction. IFI16 is essential for IFR3 signaling during HSV-1 infection and contributes to viral gene repression through heterochromatin assembly. It is also implicated in MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.