Thermo Fisher Scientific AGR2 Monoclonal Antibody (UMAB245), UltraMAB
인간 AGR2 단백질을 인식하는 UMAB245 단클론 항체로, IHC(P) 등 연구용으로 적합. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 저장 버퍼 포함. 다양한 암 연구에서 AGR2 발현 분석에 활용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB245 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21–175 of human AGR2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. AGR2 may serve as a molecular marker and potential therapeutic target for hormone-responsive breast tumors. AGR2 is ubiquitously expressed with upregulated expression in prostate, breast, lung, renal, and endometrial carcinomas. AGR2 expression is positively correlated with the estrogen receptor (ER) and negatively correlated with the epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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