Thermo Fisher Scientific F13A1 Monoclonal Antibody (UMAB243), UltraMAB
인간 F13A1 단백질을 인식하는 UMAB243 단클론 항체. IHC(P)에서 1:300 희석으로 검증됨. 정제된 무보존제 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도 유지. 연구용으로 혈액 응고 관련 단백질 분석에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:300
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB243 |
| Immunogen | Full length human recombinant protein of human F13A1 (Factor XIIIa) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The F13A1 gene encodes the coagulation factor XIII A subunit, the final zymogen activated in the blood coagulation cascade.
Plasma factor XIII is a heterotetramer of two A and two B subunits. The A subunits are catalytic, while the B subunits act as carrier molecules.
Platelet factor XIII consists of two A subunits identical to plasma A subunits. Upon thrombin cleavage and in the presence of calcium ions, factor XIII becomes active (factor XIIIa), catalyzing crosslinking between fibrin molecules to stabilize the clot.
Deficiency of factor XIII can lead to bleeding disorders, impaired wound healing, and recurrent miscarriages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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