Thermo Fisher Scientific RGR Polyclonal Antibody
RGR 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 비인간 영장류 반응성. IHC(P)에서 검증됨. 합성 펩타이드 면역원 사용, 항원 친화 크로마토그래피로 정제. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–19 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human RGR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551509 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey, Marmoset (100%)
Gorilla, Rat, Panda, Rabbit, Horse (88%)
Dog, Hamster, Elephant (81%)
Target Information
This gene encodes a putative retinal G-protein coupled receptor. It belongs to the opsin subfamily of the 7-transmembrane, G-protein coupled receptor 1 family. Like other opsins binding retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase catalyzing the conversion of all-trans-retinal to 11-cis-retinal, while the reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. Expression is limited to tissue adjacent to retinal photoreceptor cells, including the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP). Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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