Thermo Fisher Scientific Phospho-CD104 (Thr1530) Polyclonal Antibody
인간, 마우스, 랫트에서 인지되는 인테그린 베타4 Thr1530 인산화 형태를 검출하는 폴리클로날 항체. Western blot에 적합하며, 고순도 액상 형태로 제공. PBS와 글리세롤 버퍼에 보존되며 -20°C에서 안정적 보관 가능.
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Thermo Fisher Scientific Phospho-CD104 (Thr1530) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Integrin beta 4 around the phosphorylation site of Thr1530 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899225 |
Product Specific Information
This antibody detects endogenous levels of Integrin beta 4 only when phosphorylated at Thr1530.
Target Information
Integrins are heterodimers composed of alpha and beta subunits that form noncovalently associated transmembrane glycoprotein receptors. Different combinations of these subunits determine ligand-binding specificity. Integrins mediate cell-matrix and cell-cell adhesion and transmit signals regulating gene expression and cell growth.
The Integrin beta 4 subunit acts as a receptor for laminins and often associates with the alpha 6 subunit, playing a key role in invasive carcinoma biology.
Mutations in this gene are linked to epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encode distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-114589_CD104_Integrin_beta_4_P16144-1_Rabbit.svg, PA5-114589_CD104_Integrin_beta_4_P16144-1_Rabbit_PDP.jpeg)
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