Thermo Fisher Scientific Complement C4 Polyclonal Antibody
Rat C4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IP 및 Inhibition Assay에 적합함. Affinity chromatography로 정제된 액상 형태이며, PBS/BSA buffer에 보존됨. Complement C4 연구 및 면역학적 분석용으로 사용.
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Applications
Immunoprecipitation (IP)
- Tested Dilution: 1:50
Inhibition Assays (IA)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The polyclonal antibody reacts with Rat C4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091723 |
Target Information
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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