Thermo Fisher Scientific Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8198R)
Recombinant rabbit monoclonal antibody targeting Cytokeratin 6 (KRT6; isoforms a,b,c) for basal cell detection. Validated for IHC applications. High purity, unconjugated, and stored in PBS buffer. Suitable for human samples in research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT6/8198R |
| Immunogen | Recombinant fragment (around aa1–200) of human KRT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and epidermis, both in normal and hyperproliferative states.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas and is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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