Thermo Fisher Scientific Cytokeratin 6A (KRT6A) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8120R)
Basal cell marker인 Cytokeratin 6A(KRT6A)에 특이적인 recombinant rabbit monoclonal antibody. 인체 시료에 반응하며 IHC(P) 및 IHC(PFA) 실험에 적합. 고순도 Protein A/G 정제, 안정적 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Cytokeratin 6A (KRT6A) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8120R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT6/8120R |
| Immunogen | Recombinant fragment of human KRT6 (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region and are known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, as well as in epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas, and its expression is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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