Thermo Fisher Scientific Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8267R)
Cytokeratin 6/KRT6(a,b,c)을 인식하는 재조합 토끼 단클론 항체로, 기저세포 마커로 사용됩니다. 인체 시료에 반응하며 IHC(P)에서 1–2 µg/mL 농도로 사용 가능합니다. 단백질 A/G로 정제된 액상 항체로, 4°C에서 보관합니다.
- 카탈로그번호
- 3853-RBM12-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8267R)
Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT6/8267R |
| Immunogen | Recombinant fragment (around aa1–200) of human KRT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human tonsil or basal cell carcinoma (BCC)
- Cellular Location: Cytoplasm
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, including the epidermis, in both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas, and its expression is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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