Thermo Fisher Scientific Cytokeratin 6A (KRT6A) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/3997R)
Basal cell marker로서 인간 KRT6A를 인식하는 recombinant rabbit monoclonal antibody. IHC(P) 및 IHC(PFA) 실험에 최적화되어 있으며, 높은 특이성과 재현성을 제공. HEK293 발현 시스템 기반으로 정제된 고순도 항체로 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT6/3997R |
| Immunogen | Recombinant fragment of human KRT6 (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and epidermis in both normal and hyperproliferative states.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas, and its expression is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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