Thermo Fisher Scientific Cytokeratin 6A (KRT6A) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/3997R)
사이토케라틴 6A(KRT6A)를 인식하는 재조합 토끼 단클론 항체로, 기저세포 마커로 사용됩니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 인간 시료에 반응합니다. 단백질 A/G로 정제된 액상 항체로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT6/3997R |
| Immunogen | Recombinant fragment of human KRT6 (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins. Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, including the epidermis, under both normal and hyperproliferative conditions. Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas, and its expression is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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