Thermo Fisher Scientific HEXB Polyclonal Antibody
HEXB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(Paraffin) 실험에 적합. 고순도의 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the C-terminal region of human HEXB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555170 |
Target Information
Hexosaminidase B (HEXB), also designated beta-hexosaminidase B, is a tetramer of two β-A and two β-B chains and is found in lysosomes. Mutations in the HEXB gene cause Sandhoff disease (GM2-gangliosidosis type II), leading to deficient HEXB and HEXA enzyme activity and accumulation of GM2 ganglioside in the brain. This results in progressive destruction of the central nervous system. Sandhoff disease is similar to Tay-Sachs disease, but typically more severe.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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