Thermo Fisher Scientific Phospho-Kir3.1 (Ser185) Polyclonal Antibody
Phospho-Kir3.1 (Ser185) 항체로, G 단백질 조절 칼륨 채널 연구용. Western blot, IHC, ICC/IF에 적용 가능. Rabbit polyclonal IgG 형태로, 인산화 Ser185 부위에 특이적 결합. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human GIRK1/KIR31/KCNJ3 around the phosphorylation site of Ser185 (K-M-SP-Q-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555171 |
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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