Thermo Fisher Scientific IL4R Recombinant Rabbit Monoclonal Antibody (209), PE

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5 µL/test

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

209

Immunogen

Recombinant protein ecoding Human IL4R (Met1-His232). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL4R,uniProtId:P24394-1,ncbiNodeId:9606,antigenRange:1-232,antigenLength:825,antigenImageFileName:MA5-46669_IL4R_P24394-1_Rabbit.svg,antigenImageFileNamePDP:MA5-46669_IL4R_P24394-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

PE PE PE

View additional formats

• Unconjugated
• APC
• Request custom conjugation

Excitation/Emission Max

565/576 nm View spectra

Form

Liquid

Concentration

100 µg/mL

Purification

Protein A

Storage buffer

PBS with 0.5% BSA

Contains

0.03% ProClin 300

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2937741

Product Specific Information

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL4R (Met1-His232) and conjugated with PE under optimum conditions, the unreacted PE was removed.

Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Target Information

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.