Thermo Fisher Scientific TGFBR2 Recombinant Rabbit Monoclonal Antibody (16H2L4)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL
• View 2 publications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL
• View publications

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey and Rabbit.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to large rabbit immune repertoire

Target Information

Transforming Growth Factor, beta receptor 2 (TGFBR2) is a member of the TGF-beta family of receptor Serine/Threonine kinases involved in the regulation of cell proliferation.

TGFBR2 encodes the gamma subunit of the catalytic core of mitochondrial ATP synthase, which catalyzes ATP synthesis utilizing an electrochemical proton gradient across the inner membrane during oxidative phosphorylation. The enzyme complex includes:

• F1 (soluble catalytic core): composed of α, β, γ, δ, ε subunits (3α, 3β, 1 each of γ, δ, ε)
• Fo (membrane-spanning proton channel): composed of a, b, c subunits

Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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