Thermo Fisher Scientific SALL4 Recombinant Rabbit Monoclonal Antibody (15H26L3)
SALL4 단백질을 인식하는 재조합 토끼 단클론 항체로, 인간 시료에 반응하며 ICC/IF 및 ChIP assay에 적합합니다. 높은 특이성과 재현성을 제공하며, 단백질 A로 정제된 액상 형태로 제공됩니다. 줄기세포 및 암 생물학 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| ChIP assay (ChIP) | 2.5 µg × 10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 15H26L3 |
| Immunogen | Peptides corresponding to Human SALL4 (aa 7–21, 808–822, 1038–1053) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633030 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, and Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Sall4 protein, encoded by the Sall4 gene on human chromosome 20, belongs to the Spalt-like protein family. It plays a key role in somatic stem cell maintenance and serves as a stem cell biomarker. Sall4 is a zinc finger transcription factor that interacts with Oct4 and Sox2, forming a complex with Nanog to maintain pluripotency in embryonic stem cells (ESCs). It is also studied as an oncogene and tumor biomarker, with reported target genes including p53, Bmi-1, Bcl2, and XIAP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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