
Thermo Fisher Scientific RGR Polyclonal Antibody
RGR 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 및 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 광수용체 관련 연구 및 단백질 발현 분석에 적합합니다.
- 카탈로그번호
- PA576301
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RGR Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human RGR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720028 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
This gene encodes a putative retinal G-protein coupled receptor and is a member of the opsin subfamily of the 7-transmembrane, G-protein coupled receptor 1 family. Like other opsins that bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain.
The protein functions as a photoisomerase, catalyzing the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. It is expressed in tissue adjacent to retinal photoreceptor cells, including the retinal pigment epithelium and Mueller cells.
Mutations in this gene may be associated with autosomal recessive or dominant retinitis pigmentosa (arRP and adRP). Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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