Thermo Fisher Scientific Phospho-c-Met (Tyr1349) Monoclonal Antibody (S.960.2)
Phospho-c-Met (Tyr1349) 단백질의 인산화 상태를 검출하는 Rabbit monoclonal antibody입니다. Western blot에 최적화되어 있으며 Human, Mouse, Rat 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 -20°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-c-Met (Tyr1349) Monoclonal Antibody (S.960.2)
Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S.960.2 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr1349 of human Met |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10978558 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation by its ligand, MET interacts with PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3, leading to activation of signaling cascades such as RAS-ERK, PI3K-AKT, and PLCγ-PKC.
MET plays critical roles in embryonic development, including gastrulation, muscle and neuron formation, angiogenesis, and kidney development. In adults, it contributes to wound healing, organ regeneration, and tissue remodeling. Dysregulation of MET is associated with cancers including gastric, renal, and breast, making it a key target for cancer therapeutics and diagnostic research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.