Thermo Fisher Scientific Phospho-PDGFRB (Tyr771) Monoclonal Antibody (G.69.10)
Phospho-PDGFRB (Tyr771) 단일클론 항체로 인간 및 생쥐 시료에 반응합니다. Western blot에 최적화되어 있으며, 친화 크로마토그래피로 정제된 액상 항체입니다. -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G.69.10 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr771 of human PDGF receptor β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10978046 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PDGFRB (Platelet-Derived Growth Factor Receptor Beta) is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for mesenchymal cells. The receptor can form homodimers or heterodimers with PDGF receptor alpha depending on the ligand. The PDGFRB gene, located on chromosome 5, is near genes for GM-CSF and M-CSF receptor, potentially involved in the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) with ETV6 results in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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