Thermo Fisher Scientific IL-6 Recombinant Superclonal Antibody (4HCLC)
Thermo Fisher의 IL-6 Recombinant Superclonal Antibody(4HCLC)는 인간 IL-6 단백질을 인식하는 재조합 Superclonal 항체로, 높은 민감도와 일관된 로트 간 재현성을 제공합니다. WB 및 ELISA에 적합하며, 단백질 A 정제 및 PBS 완충액에 0.09% sodium azide가 포함되어 있습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 4–5 µg/mL |
| ELISA | 1:50–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 4HCLC |
| Immunogen | Protein corresponding to amino acids 30–212 of human IL-6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532536 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Each lot can be reproduced with the same antibody population, eliminating biological variability typically found in polyclonal antibodies.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
IL-6 encodes a cytokine involved in inflammation and B cell maturation. It acts as an endogenous pyrogen, inducing fever in autoimmune or infectious conditions. IL-6 is primarily expressed at sites of acute and chronic inflammation, secreted into serum, and triggers transcriptional inflammatory responses through the IL-6 receptor alpha.
Elevated IL-6 levels are linked to various inflammation-associated diseases, including diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and COVID-19 (SARS-CoV-2 infection).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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