Thermo Fisher Scientific Human HAX1 beta Synthetic Peptide
인간 HAX1 베타 합성 펩타이드로, PA5-20650 항체의 블로킹 펩타이드로 사용 가능. Hax1 단백질의 아미노 말단 10개 아미노산에 해당. 항체 검증 및 세포 사멸 연구에 활용. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0770
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human HAX1 beta Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 10 amino acids near the amino terminus of human Hax1 isoform b.
PEP-0770 can be used as a blocking peptide with polyclonal antibody PA5-20650.
Target Information
The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay based on its ability to bind to the hematopoietic cell-specific protein 1 (HS-1).
Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains.
It has been shown to interact with HIV viral protein R (Vpr), which is linked to T-cell apoptosis through activation of caspases 3 and 9.
Other studies indicate that Hax1-mediated processing of HtrA2 (Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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