Thermo Fisher Scientific Nestin Monoclonal Antibody (10C2), Alexa Fluor 555
Alexa Fluor 555 형광 표지된 Nestin 단클론 항체로 인간 및 마우스 시료에 반응. 신경줄기세포 및 종양 내 혈관신생 연구에 활용 가능. WB, ICC/IF 등 다양한 응용에 적합하며 높은 특이성과 안정적 형광 신호 제공.
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Applications
Western Blot (WB)
Tested Dilution: Not specified
View 1 publicationImmunocytochemistry (ICC/IF)
Tested Dilution: 5 µg/mL
View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10C2 |
| Immunogen | Human nestin protein (residues 1464–1614) |
| Conjugate | Alexa Fluor™ 555 |
| Excitation / Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1.0 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Dry ice (international) |
| RRID | AB_2723400 |
Additional Formats
Product Specific Information
MA1-110 has been successfully utilized in Western Blot, immunocytochemistry, flow cytometry, and immunofluorescence applications in human samples.
Target Information
Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells.
It serves as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells.
Nestin is also a superior angiogenic marker for evaluating neovascularity in tumors.
Highly specific antibodies to human Nestin assist in characterizing progenitor cell differentiation, enhancing therapeutic potential in CNS disease treatment, and identifying neuroepithelial tumor cells.
Nestin expression has been observed in pancreatic hematopoietic stem cell populations and is considered a novel angiogenesis marker in proliferating endothelial cells of colorectal cancer tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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