Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) (Transcription Factor) Monoclonal Antibody (NR5A1/3420)
인체 SF-1 단백질을 인식하는 Mouse monoclonal 항체로, IHC(P), IHC(PFA), Peptide Array에 적합합니다. Protein A/G 정제, 200 µg/mL 농도의 액상 형태이며, PBS(pH 7.4) 버퍼에 0.05% BSA와 sodium azide를 포함합니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NR5A1/3420 |
| Immunogen | Recombinant fragment (around aa220–461) of human SF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2), common to many nuclear steroid receptors, which are necessary for interactions with coactivators and corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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