Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) (Transcription Factor) Monoclonal Antibody (NR5A1/3420)
인체 SF-1 단백질을 인식하는 마우스 단클론 항체로, IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 적합합니다. 단백질 A/G 정제, PBS(pH 7.4) 용액 형태이며 보존제 무첨가. 내분비계 발달 및 스테로이드 생성 관련 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NR5A1/3420 |
| Immunogen | Recombinant fragment (around aa220–461) of human SF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of steroidogenic enzymes from the cytochrome P450 family. It contains two activation function domains, AF1 and AF2, which facilitate interactions with other nuclear receptors and coactivators such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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