Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183) Polyclonal Antibody
JNK1/JNK2/JNK3 인산화(Thr183) 부위를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피 정제, 고순도(>95%), 액상 형태로 4°C 또는 -20°C 보관.
- 카탈로그번호
- PA536832
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Threonine 183 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553765 |
Product Specific Information
- Detects endogenous JNK protein at molecular weights of 46 kDa and 54 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. These Serine-threonine kinases are activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK is involved in numerous cellular processes including proliferation, differentiation, transcription regulation, and development.
JNK pathways are activated by stress and inflammatory signals, and expressed as ten different isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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