
Thermo Fisher Scientific AK1 Monoclonal Antibody (OTI8A1), TrueMAB
인간 AK1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 동결건조 형태이며 PBS 버퍼에 트레할로스 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific AK1 Monoclonal Antibody (OTI8A1), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2500–1:5000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Full length human recombinant protein of human AK1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Adenylate kinase is an enzyme that regulates adenine nucleotide composition within cells by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes—AK1, AK2, and AK3—have been identified in vertebrates:
- AK1: Found in cytosol of skeletal muscle, brain, and erythrocytes
- AK2 / AK3: Found in mitochondria of tissues such as liver and heart
AK1 mutations are associated with nonspherocytic hemolytic anemia due to reduced catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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