Thermo Fisher Scientific AK1 Monoclonal Antibody (OTI18C7), TrueMAB
AK1 단백질을 인식하는 Mouse 단일클론 항체로 Western blot, ICC/IF, Flow Cytometry에 적합. Human 시료 반응성. 동결건조 형태로 제공되며, PBS(8% trehalose) 버퍼에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI18C7 |
| Immunogen | Full length human recombinant protein of human AK1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Adenylate kinase regulates the adenine nucleotide composition within cells by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes—AK1, AK2, and AK3—exist in vertebrates.
- AK1: Found in cytosol of skeletal muscle, brain, and erythrocytes
- AK2 / AK3: Located in mitochondria of tissues such as liver and heart
Mutations in the AK1 gene are associated with nonspherocytic hemolytic anemia due to reduced catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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