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Thermo Fisher Scientific GAD1 Monoclonal Antibody (OTI3H2), TrueMAB
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GAD1 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 인간 및 개 시료에 반응하며, 동결건조 형태로 제공됩니다. 연구용으로 GABA 합성 관련 단백질 분석에 활용됩니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 01:42
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Thermo Fisher Scientific CF500328 GAD1 Monoclonal Antibody (OTI3H2), TrueMAB 100 ug pk판매 단위 pk ·
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784,000원VAT 포함 862,400원
Thermo Fisher Scientific · Thermo Fisher Scientific GAD1 Monoclonal Antibody (OTI3H2), TrueMAB
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 4 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H2 |
| Immunogen | Full-length human recombinant GAD1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
GAD-65 and GAD-67 are members of the group II decarboxylase family, catalyzing the rate-limiting step in GABA (gamma-aminobutyric acid) synthesis from L-glutamic acid.
- Localization: GAD-65 is associated with synaptic vesicle membranes, while GAD-67 is distributed throughout the cell.
- Function: GAD-67 maintains basal GABA levels; GAD-65 is transiently activated under increased neurotransmission demand.
- Significance: Loss of GAD-65 impairs GABA neurotransmission; loss of GAD-67 is lethal.
Two isoforms exist due to alternative splicing: predominant GAD-67 and minor GAD-25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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