Thermo Fisher Scientific ASAP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ASAP1 protein. Validated for Western blot and immunoprecipitation. Predicted cross-reactivity with mouse and rat. Liquid form, unconjugated, stored at 4°C. Suitable for research use only.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ASAP1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 750 and 800 of human ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
ASAP1, also known as Development and differentiation enhancing factor 1, is a protein containing two ANK repeats, an Arf-GAP domain, a PH domain, and a SH3 domain.
ASAP1 forms homodimers and interacts with SRC and CRK, with activity stimulated by phosphatidylinositol 4,5-biphosphate (PIP2).
It exhibits PIP2-dependent GTPase-activating protein activity for ARF1 and ARF5, with lesser activity toward ARF6.
ASAP1 may coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling, functioning in signal transduction processes such as fibroblast differentiation into adipocytes.
It is widely expressed in most tissues and is considered a proto-oncogene involved in invasive breast cancer and other malignant tumors, including uveal melanomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.