Thermo Fisher Scientific SSB Monoclonal Antibody (OTI1E11), TrueMAB
SSB 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, Flow cytometry, IP에 적합합니다. Human, Mouse, Rat, Dog 시료에 반응하며, 고순도의 affinity chromatography 정제 항체입니다. Lyophilized 형태로 -20°C 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human SSB expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
La (SSB) protein is involved in various aspects of RNA metabolism, including:
- Binding and protecting 3′ UUU(OH) elements of newly RNA polymerase III-transcribed RNA
- Processing 5′ and 3′ ends of pre-tRNA precursors
- Acting as an RNA chaperone
- Binding viral RNAs associated with hepatitis C virus
La protein was originally defined by its reactivity with autoantibodies from patients with Sjögren syndrome and systemic lupus erythematosus.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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