Thermo Fisher Scientific SSB Monoclonal Antibody (OTI9D6), TrueMAB
SSB 단백질을 표적으로 하는 마우스 모노클로날 항체로, Western blot, IHC, ICC/IF, Flow cytometry, IP 등 다양한 응용에 적합함. 무보존제, 동결건조 형태로 제공되며, RNA 대사 관련 연구용으로 사용됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9D6 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human SSB expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
La (SSB) protein is involved in multiple aspects of RNA metabolism, including:
- Binding and protecting 3'-UUU(OH) elements of newly transcribed RNA polymerase III products
- Processing 5' and 3' ends of pre-tRNA precursors
- Acting as an RNA chaperone
- Binding viral RNAs associated with hepatitis C virus
La protein was originally identified by its reactivity with autoantibodies from patients with Sjögren syndrome and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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