Thermo Fisher Scientific CD2 Monoclonal Antibody (OTI4E4), TrueMAB
CD2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, 인간 시료에 반응합니다. Western blot과 Flow cytometry에 사용 가능하며, carrier-free 형태로 재구성 및 결합 실험에 적합합니다. PBS 버퍼에 동결건조되어 장기 보관이 용이합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E4 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human CD2 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
- For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD2 (LFA-2) is a monomeric surface antigen (MW 45–58 kDa) expressed on human T-lymphocytes and some NK cells, but not on B lymphocytes. It plays a key role in T-cell adhesion via interaction with CD58, stabilizing cell-cell contact during immune responses. CD2 expression increases upon T-cell activation, enhancing adhesion and mobility. CD2 deficiency is linked to reduced intestinal inflammation and certain immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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