Thermo Fisher Scientific NMDAR2A Recombinant Rabbit Monoclonal Antibody (JA31-20)
NMDAR2A 단백질을 인식하는 recombinant rabbit monoclonal 항체로, Western blot 및 IHC(P) 검증 완료. 높은 특이성과 재현성을 제공하며, lot 간 일관성이 우수함. Protein A 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA31-20 |
| Immunogen | Synthetic peptide within Human NMDAR2A aa 1356–1405 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809988 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened to select optimal candidates for production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the large rabbit immune repertoire
Target Information
N-methyl-D-aspartate (NMDA) receptors are ionotropic glutamate-gated ion channels involved in long-term potentiation, a mechanism underlying memory and learning.
NMDA receptor channels are heteromers composed of the NMDAR1 (GRIN1) subunit and one or more NMDAR2 subunits:
- NMDAR2A (GRIN2A)
- NMDAR2B (GRIN2B)
- NMDAR2C (GRIN2C)
- NMDAR2D (GRIN2D)
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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