Thermo Fisher Scientific Osteonectin (SPARC) Monoclonal Antibody (ON1-1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-10 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1-10 µg/mL

-

ELISA (ELISA)

1-10 µg/mL

-

Product Specifications

Species Reactivity

Bovine, Human, Pig, Rabbit

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

ON1-1

Immunogen

Bovine bone osteonectin (SPARC)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5-1.0 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 50 µL of distilled water (2 mg/mL final concentration).

Target Information

SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.