Thermo Fisher Scientific CD4 Monoclonal Antibody (SK3 (SK-3)), Alexa Fluor 532, eBioscience
인간 CD4 항원에 특이적인 SK3 클론 단일클론 항체로, Alexa Fluor 532 형광체가 결합된 제품입니다. Flow cytometry 분석용으로 최적화되어 있으며 HIV 수용체 연구에 활용 가능합니다. Green laser(532 nm)에서 여기되어 561 nm에서 방출됩니다.
- 카탈로그번호
- 58-0047-42
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD4 Monoclonal Antibody (SK3 (SK-3)), Alexa Fluor 532, eBioscience
Thermo Fisher Scientific CD4 Monoclonal Antibody (SK3 (SK-3)), Alexa Fluor 532, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.03 µg)/test
Publications: View 7 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Alexa Fluor™ 532, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SK3 (SK-3) |
| Conjugate | Alexa Fluor™ 532 |
| Excitation / Emission Max | 534 / 553 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11218872 |
Product Specific Information
Description:
The SK3 monoclonal antibody reacts with human CD4, a 59-kDa cell surface receptor expressed by thymocytes, mature T helper cells, and at low levels on monocytes. CD4 serves as a receptor for HIV, and SK3 blocks HIV binding and mixed lymphocyte reactions. SK3 and RPA-T4 antibodies recognize distinct epitopes.
Applications Reported:
Use in flow cytometric analysis.
Applications Tested:
Pre-titrated and validated for flow cytometry on normal human peripheral blood cells. Recommended usage: 5 µL (0.03 µg)/test. A test is defined as staining a cell sample in a final volume of 100 µL (10⁵–10⁸ cells/test).
Fluorophore Information:
Alexa Fluor® 532 is excited with the Green laser (532 nm) and emits at 561 nm. Not compatible with the Yellow-Green laser (561 nm). Recommended filter: 560/14 band pass.
Excitation: 532 nm
Emission: 561 nm
Laser: Green Laser
Target Information
The CD4 antigen recognizes MHC class II molecules and acts as a co-receptor for HIV. It is primarily expressed in T helper cells, with additional expression in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and certain brain and gut regions. CD4 aids early T-cell activation via interaction with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts exist (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
Additional Available Formats
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Brilliant UV 395
- Brilliant UV 496
- Brilliant UV 563
- Brilliant UV 737
- Brilliant UV 805
- Brilliant Violet 421
- Brilliant Violet 605
- eFluor 450
- FITC
- NovaFluor Blue, Red, Violet, Yellow series (various wavelengths)
- PE, PE-Cyanine5.5, PE-Cyanine7, PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436, 600, 645, 702, 780
- Request custom conjugation available
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.