Thermo Fisher Scientific Phospho-NFkB p65 (Ser536) Monoclonal Antibody (E.949.5)
NFkB p65 (Ser536) 인산화형을 특이적으로 검출하는 Thermo Fisher Scientific의 단클론 항체. Western blot에 최적화되어 있으며, 인간 및 설치류 등 다양한 종에 반응. 액상 형태로 고순도 정제되어 안정적인 신호 검출 제공.
- 카탈로그번호
- MA515181
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-NFkB p65 (Ser536) Monoclonal Antibody (E.949.5)
Applications
- Western Blot (WB): Tested dilution 1:1,000
- View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mink, Mouse, Non-human primate, Rat |
| Published Species | Human, Mink, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.949.5 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer536 of human NF-kappaB p65 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1400 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982265 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with the p50 subunit or other related proteins.
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and located on chromosome 11 in humans. NF-kB p65 (RelA) belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits. Upon TNF-α binding to its receptor, IKK is phosphorylated, leading to IκB phosphorylation and degradation, thereby activating NF-kB. NF-kB p65 plays a crucial role in transcriptional regulation of the immunoglobulin kappa gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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