
Thermo Fisher Scientific Cannabinoid Receptor 1 Recombinant Rabbit Monoclonal Antibody (PSH02-43)
Recombinant rabbit monoclonal antibody targeting human Cannabinoid Receptor 1 (CR1). Validated for WB and IHC (P) applications. High specificity and reproducibility with Protein A purification. Suitable for brain tissue studies. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PSH02-43 |
| Immunogen | Recombinant protein within human Cannabinoid receptor 1 (aa 1–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3099397 |
Product Specific Information
- Tissue Specificity: Human brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brain tissue lysate, rat cerebellum tissue lysate, mouse hippocampus tissue, rat hippocampus tissue.
- Positive Control: Human and rodent brain and cerebellum tissues.
- Subcellular Location: Cell membrane, membrane raft, mitochondrion outer membrane, axon, presynapse.
- Predicted Band Size: 53 kDa.
Target Information
This gene encodes one of two cannabinoid receptors. Cannabinoids, including delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. These receptors are G-protein coupled receptors that inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. Both receptors are involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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