Thermo Fisher Scientific TRIM21 Recombinant Rabbit Monoclonal Antibody (PSH02-56)
TRIM21 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC, Flow Cytometry에 적합합니다. 인간 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 다양한 세포 및 조직에서 TRIM21 발현 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 – 1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 – 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PSH02-56 |
| Immunogen | Recombinant protein within human TRIM21 aa 1–475 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3099396 |
Product Specific Information
- Tissue Specificity: Fetal and adult heart, fetal lung
- Positive Control: HeLa cell lysate, IFN-alpha treated HeLa lysate, A549, 293T, U-2 OS cell lysates, human spleen tissue, human tonsil tissue
- Subcellular Location: Cytoplasm, cytoplasmic vesicle, autophagosome, nucleus, P-body
- Predicted Band Size: 54 kDa
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein complex, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus and interacts with autoantigens in patients with Sjögren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants have been described, but only one full-length form has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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