Thermo Fisher Scientific PPBP Polyclonal Antibody
Thermo Fisher Scientific의 PPBP Polyclonal Antibody는 인간 단백질에 반응하는 토끼 유래 항체입니다. Western blot, IHC, ELISA에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결 건조 형태로 제공되며, 재구성 시 500 µg/mL 농도로 사용 가능합니다.
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- PA579853
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| ELISA | 0.1–0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human NAP2 recombinant protein (Position: S55–D128) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746968 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Members of the α-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a Cys-X-Cys motif and are chemotactic for neutrophils.
The platelet basic protein (PBP), a member of this family, is stored in platelet α-granules and released upon activation. Proteolytic cleavage of PBP generates peptides such as mature PBP, connective tissue-activating peptide III (CTAP III, also known as low affinity platelet factor IV, LA-PF4), β-thromboglobulin (β-TG), and neutrophil-activating peptide 2 (NAP-2).
These molecules play roles in inflammation and wound healing, with NAP-2 specifically activating chemotaxis and degranulation in neutrophils. The human PBP gene is located on chromosome 4q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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